The heat sterilization method uses high temperature to coagulate or denature the bacterial protein, the enzyme loses activity, impede metabolism, and cause bacteria death. Thermal sterilization methods include moist heat sterilization and dry heat sterilization. Damp heat can cause the bacterial protein to coagulate and deform; dry heat can oxidize, denature, carbonize and concentrate the electrolyte to cause cell death. The heat sterilization is convenient, the effect is good, and it is non-toxic. It is the main sterilization method used by the hospital disinfection supply center. The pressure steam sterilization method is the preferred sterilization method for wet and heat resistant medical devices.
Low temperature sterilization
The low temperature sterilization method is a method of killing pathogenic microorganisms by using chemical sterilizing agent. The temperature required for sterilization of chemicals is low, and is often referred to as low temperature sterilization method or chemical sterilization method. The chemical disinfectant used in low-temperature sterilization can kill all microorganisms and achieve the level of sterilization assurance. Such chemical agents with sterilization effects include formaldehyde, glutaraldehyde, ethylene oxide, peracetic acid and the like. Chemical sterilization is used for sterilization of instruments that cannot withstand high temperature, damp heat materials.
Commonly used low temperature sterilization methods include hydrogen peroxide plasma low temperature sterilization, ethylene oxide sterilization, and low temperature formaldehyde steam sterilization.