Differentiation between 3-part hematology analyzer and 5-part hematology analyzer
1, The difference between the instrument detection principle
Most of the three-part instruments adopt electrical impedance detection technology, which consists of signal generator, amplifier, discriminator, threshold regulator, detection and counting system and automatic compensation device. Most of the five-part products adopt light scattering detection technology, mainly by laser source(Multiple argon-ion lasers are used to provide monochromatic light), detection zones (mainly consisting of devices in the form of sheath flow to ensure that cell suspensions form a single array of cell flows in the detection flow), detectors scattered light detector is a photodiode for collecting scattered light signals generated by laser irradiation of cells; the fluorescence detector is a photomultiplier tube for receiving fluorescent signals generated by fluorescent irradiation of cells after laser irradiation).
2, The difference between Leukocyte Classification methods
Three-part product divides white blood cells into lymphocytes, monocyte, and granulocyte; the five-part instrument divides white blood cells into lymphocytes, monocyte, and granulocyte (neutrophil, eosinophil, and basophil).